False alarm on this one - the EN and GPIO pins were accidentally swapped despite the labels.

I'm using a programmer that works fine on ESP32 designs.

https://github.com/gcormier/eflashy32
https://i.imgur.com/MoTuhNt.png

I have had no issues with this to program ESP32-WROOM-32 designs.

When trying to use this to program ESP32-S2 modules, it doesn't work.

The serial is OK - if I apply ...