Thank you for all your responses. I tried a few things but nothing worked.

Things I tried
adding a RC circuit for CHIP_PU
Powering the board with external 3.3V
Doubling C3 and C2 to 16pF each with two 8pF parallel (because of the stray capacity https://forum.arduino.cc/t/stray-capacitance-on ...

Hello,

I have a problem with my own created pcb.


IMG_2972.png

This is my pcb design


Explanation:
ESP32-S3 SoC
5V to 3.3V with MCP1700
USB with D+ and D- to GPIO19/GPIO20
40MHz Crystal to XTAL_N and XTAL_P
R2 is my boot-button, I solder the pads together if I need to enable the ...