Just to be sure I don't mess up on the project, on the S3-MINI-1-N4R2 i should be carefull with:

IO0,3,45,46: STRAPPING PINS. Operation described in Boot configuration on datasheet
RX0, TX0: Bootloader/debug UART
IO19,20: USB pins
IO26 - Don't use "For modules with ordering codes ending with -N4R2 ...